Tell Me When It's Over
An Insider's Guide to Deciphering Covid Myths and Navigating Our Post-Pandemic World
Paul A.Offit - Author
From one of the world’s top virologists, the definitive guide to understanding and navigating COVID-19.
Three years on, COVID is clearly here to stay. So what do we do now? Drawing on his expertise as one of the world’s top virologists, Dr. Paul Offit helps weary readers address that crucial question in this brief, definitive guide.
As a member of the FDA Vaccine Advisory Committee and a former member of the Advisory Committee for Immunization Practices to the CDC, Offit has been in the room for the creation of policies that have affected hundreds of millions of people.In these pages, he marshals the power of hindsight to offer a fascinating frontline look at where we were, where we are, and where we’re heading in the now-permanent fight against the disease.
Accompanied by a companion website populated with breaking news and relevant commentary, this book contains everything you need to know to navigate COVID going forward. Offit addresses fundamental issues like boosters, immunity induced by natural infection, and what it means to be fully vaccinated. He explores the dueling origin stories of the disease, tracing today’s strident anti-vax rhetoric to twelve online sources and tracking the fallout. He breaks down long COVID - what it is, and what the known treatments are. And he looks to the future, revealing whether we can make a better vaccine, whether it should be mandated, and providing a crucial list of fourteen takeaways to eradicate further spread.
Filled with pragmatic analysis and sensible advice, TELL ME WHEN IT’S OVER is for anyone interested in finding new solutions to the new normal.
Breaking Through: My Life in Science
by Katalin Karikó
A powerful memoir from Katalin Karikó, winner of the 2023 Nobel Prize in Physiology or Medicine, whose decades-long research led to the COVID-19 vaccines
Katalin Karikó has had an unlikely journey. The daughter of a butcher in postwar communist Hungary, Karikó grew up in an adobe home that lacked running water, and her family grew their own vegetables. She saw the wonders of nature all around her and was determined to become a scientist. That determination eventually brought her to the United States, where she arrived as a postdoctoral fellow in 1985 with $1,200 sewn into her toddler’s teddy bear and a dream to remake medicine.
Karikó worked in obscurity, battled cockroaches in a windowless lab, and faced outright derision and even deportation threats from her bosses and colleagues. She balked as prestigious research institutions increasingly conflated science and money. Despite setbacks, she never wavered in her belief that an ephemeral and underappreciated molecule called messenger RNA could change the world. Karikó believed that someday mRNA would transform ordinary cells into tiny factories capable of producing their own medicines on demand. She sacrificed nearly everything for this dream, but the obstacles she faced only motivated her, and eventually she succeeded.
Karikó’s three-decade-long investigation into mRNA would lead to a staggering achievement: vaccines that protected millions of people from the most dire consequences of COVID-19. These vaccines are just the beginning of mRNA’s potential. Today, the medical community eagerly awaits more mRNA vaccines—for the flu, HIV, and other emerging infectious diseases.
Breathless
The Scientific Race to Defeat a Deadly Virus
by David Quammen
2022 National Book Award Finalist.
The story of the worldwide scientific quest to decipher the coronavirus SARS-CoV-2, trace its source, and make possible the vaccines to fight the Covid-19 pandemic.
David Quammen expertly shows how strange new viruses emerge from animals into humans as we disrupt wild ecosystems, and how those viruses adapt to their human hosts, sometimes causing global catastrophe. He explains why this coronavirus will probably be a “forever virus,” destined to circulate among humans and bedevil us endlessly, in one variant form or another. As scientists labor to catch it, comprehend it, and control it, with their high-tech tools and methods, the virus finds ways of escape.
Based on interviews with nearly one hundred scientists, including leading virologists in China and around the world, Quammen explains that:
-Infectious disease experts saw this pandemic coming
-Some scientists, for more than two decades, warned that “the next big one” would be caused by a changeable new virus—very possibly a coronavirus—but such warnings were ignored for political or economic reasons
-The precise origins of this virus may not be known for years, but some clues are compelling, and some suppositions can be dismissed
by Brian Dean Abramson (Author), John R. Thomas (Author), Peter O. Safir (Author), AHLA (Author)
This treatise provides thorough coverage of all issues encountered in the practice of the law related to vaccines and vaccination, from product development and intellectual property protections, to regulation, public mandates, and vaccine injury claims. Vaccine, Vaccination, and Immunization Law will be invaluable not only to lawyers and business professionals in the health care industry, but also to regulators, public health officials, and scientific researchers. Vaccine, Vaccination, and Immunization Law covers the wide range of laws and issues that impact the field, including: FDA oversight, enforcement, and regulation of the research and development process. Public mandates, including mandatory child vaccinations, opposition, and the legal consequences of failure to vaccinate, as well as medical, religious, and philosophical exemptions. State-by-state coverage of each jurisdiction's common requirements and unique legal characteristics related to childhood and adult vaccinations, state exemptions, administration of vaccines, and isolation and quarantine matters.
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The History of Vaccines is the College’s award-winning website that provides in-depth information on the development, use, and delivery of vaccines within a historical context. The target audiences for The History of Vaccines include parents making immunization decisions for their children; students in high school and college biology, health, and history courses; and healthcare providers.
The story of viruses and humanity is a story of fear and ignorance, of grief and heartbreak, and of great bravery and sacrifice. Michael Oldstone tells all these stories as he illuminates the history of the devastating diseases that have tormented humanity, focusing mostly on the most famous viruses. Oldstone begins with smallpox, polio, and measles. Nearly 300 million people were killed by smallpox in this century alone and the author presents a vivid account of the long campaign to eradicate this lethal killer. Oldstone then describes the fascinating viruses that have captured headlines.
The struggle against deadly microbes is endless. Diseases that have plagued human beings since ancient times still exist, new maladies make their way into the headlines, we are faced with vaccine shortages, and the threat of germ warfare has reemerged as a worldwide threat. In this riveting account, medical historian Howard Markel takes an eye-opening look at the fragility of the American public health system. He tells the distinctive stories of six epidemics–tuberculosis, bubonic plague, trachoma, typhus, cholera, and AIDS–to show how our chief defense against diseases from outside the United States has been to attempt to deny entry to carriers. He explains why this approach never worked, and makes clear that it is useless in today’s world of bustling international travel and porous borders.Give customers a reason to do business with you.
A #1 New York Times bestselling author and award-winning Wall Street Journal investigative journalist lauded for his “bravura storytelling” (Gary Shteyngart) and “first-rate” reporting (The New York Times), Zuckerman takes us inside the top-secret laboratories, corporate clashes, and high-stakes government negotiations that led to effective shots. Deeply reported and endlessly gripping, this is a dazzling, blow-by-blow chronicle of the most consequential scientific breakthrough of our time. It’s a story of courage, genius, and heroism. It’s also a tale of heated rivalries, unbridled ambitions, crippling insecurities, and unexpected drama. A Shot to Save the World is the story of how science saved the world.
For those who could read between the lines, the censored news out of China was terrifying. But the president insisted there was nothing to worry about. Fortunately, we are still a nation of skeptics. Fortunately, there are those among us who study pandemics and are willing to look unflinchingly at worst-case scenarios. Michael Lewis’s taut and brilliant nonfiction thriller pits a band of medical visionaries against the wall of ignorance that was the official response of the Trump administration to the outbreak of COVID-19.
The bestselling author of Leonardo da Vinci and Steve Jobs returns with a compelling account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code.
The classic personal account of Watson and Crick’s groundbreaking discovery of the structure of DNA, now with an introduction by Sylvia Nasar, author of A Beautiful Mind. By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science’s greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.
Magisterial in its breadth of perspective and depth of research, The Great Influenza provides us with a precise and sobering model as we confront the epidemics looming on our own horizon. As Barry concludes, "The final lesson of 1918, a simple one yet one most difficult to execute, is that...those in authority must retain the public's trust. The way to do that is to distort nothing, to put the best face on nothing, to try to manipulate no one. Lincoln said that first, and best. A leader must make whatever horror exists concrete. Only then will people be able to break it apart".
Vaccines save millions of lives every year, and one man, Maurice Hilleman, was responsible for nine of the big fourteen. Paul Offit recounts his story and the story of vaccines. Maurice Hilleman discovered nine vaccines that practically every child gets, rendering formerly dread diseases, including often devastating ones such as mumps and rubella, practically forgotten. Paul A. Offit, a vaccine researcher himself, befriended Hilleman and, during the great man’s last months, interviewed him extensively about his life and career.
When scientists proved in 1984 that HIV causes AIDS, a vaccine race spun into action. But the sprint to develop an AIDS vaccine now more closely resembles a crawl. Jon Cohen elucidates the forces that have hindered the search: unforeseen scientific obstacles, clashing personalities, the uncertain marketplace, haphazard political organization, and serious ethical dilemmas. Beyond a powerful critique, Cohen also offers specific recommendations for accelerating the effort. "An important book not only for the now but for the future of this epidemic and those to come.", Dr. Robert Gallo.
CNN chief medical correspondent Sanjay Gupta, MD, offers an accessible, data-packed answer to our biggest questions about Covid-19: What have we learned about this pandemic and how can we prepare for—or prevent—the next one?
Special Coverage of Vaccines and Vaccination. As America’s favorite frontline Covid-19 health journalist, Dr. Sanjay Gupta has barely left his primetime seat in his makeshift studio basement since the pandemic began. He’s had the insider of insider access to the drama’s unfolding, including exclusive conversations with the world’s top public health experts and behind-the-scenes scientists racing to find treatments and cures. And now he’s sharing what he’s learned in a book that will answer not only all our questions about what happened, but also about how our world will change in the years ahead, even once we’re back to “normal.”
Franky Franklin, son of Ben Franklin
In Cotton Mather’s time (1720) inoculation was introduced in America. One such evangelist for inoculation was Benjamin Franklin. Along with several other founders — including George Washington, John Adams and Thomas Jefferson — Franklin himself was persuaded. Yet he still had a tragic relationship with smallpox inoculation. As the disease was sweeping through Philadelphia in 1736, he and his wife, Deborah, initially decided not to inoculate their 4-year-old son Francis, known as Franky. The boy was sick with a cold and the Franklins worried that his body would not be able to handle the side effects of inoculation. Soon, though, Franky contracted smallpox and died. “This is the great tragedy of Franklin’s life,” Burns told me. “Deborah and Benjamin Franklin were just beset by this mistake they made even though it was completely understandable.” Watch the Burns-posted six-minute “extra” film clip about Franky and inoculation. In April 2022, PBS will air Burns’s new documentary, “Benjamin Franklin.”
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